Pet Evidence PROJECT

Supplement Finder results

Cognition/brain health supplements for dogs

Products are grouped by active ingredient. Evidence labels describe the ingredient for this health goal and species — never an individual product.

NASC-certified products

Availability and commerce data appear only when published by the CMS.

8 products

Medium-chain triglycerides (MCT)

Moderate evidence

Ketone-based alternative brain fuel. Multiple randomized controlled trials show cognitive improvement in aged or epileptic dogs, including an independent double-blind crossover using MCT oil supplementation. The strongest data come from MCT-enriched diets at substantial inclusion (roughly 5.5 to 9 percent of calories), so a small oil supplement may not reach the studied intake.

Brain Boost (Organic MCT Oil)

Dr. Buzby's Innovations, LLC

Brain Boost (Organic MCT Oil)

Liquid/Oil

NASC-certified manufacturer

Verified product details

  • Form: Liquid/Oil
  • Serving size: Mixed into food twice daily

Retailer availability

Retailer links and current prices are not available for this product yet.

Antioxidant blend

Emerging evidence

Antioxidant-fortified diets and supplements (vitamin E and C, selenium, flavonoids, carotenoids, sometimes with phosphatidylserine or omega-3) have shown modest cognitive benefit in aged dogs and in canine cognitive dysfunction. Evidence is mostly small, often industry-linked trials and diet studies rather than isolated antioxidant supplements, so the signal is real but weak and hard to attribute to the antioxidants alone.

Senilife

Ceva Animal Health

Senilife

Capsule

NASC-certified manufacturer

Verified product details

  • Form: Capsule
  • Serving size: 1 capsule/day

Retailer availability

Retailer links and current prices are not available for this product yet.

SAMe (S-adenosylmethionine)

Emerging evidence

Studied for canine cognitive dysfunction with some behavioral improvement; limited.

Denamarin

Nutramax

Denamarin

Tablet

NASC-certified manufacturer

Verified product details

  • 90/225/425 SAMe per 1 Tablet
  • Form: Tablet
  • Serving size: 1 Tablet (enteric-coated)

Retailer availability

Retailer links and current prices are not available for this product yet.

Hepato Support

Animal Necessity, LLC

Hepato Support

Capsule

NASC-certified manufacturer

Verified product details

  • 90-225 SAMe per 1 Capsule
  • Form: Capsule
  • Serving size: 1 Capsule

Retailer availability

Retailer links and current prices are not available for this product yet.

SAMe Liver Health

Nutri-Vet

SAMe Liver Health

Tablet

NASC-certified manufacturer

Verified product details

  • 225 mg SAMe per 1 Tablet
  • Form: Tablet
  • Serving size: 1 Tablet

Retailer availability

Retailer links and current prices are not available for this product yet.

SAMe-225 / SAMe-425

Pet Health Solutions

SAMe-225 / SAMe-425

Tablet

NASC-certified manufacturer

Verified product details

  • 225/425 SAMe per 1 Tablet
  • Form: Tablet
  • Serving size: 1 Tablet

Retailer availability

Retailer links and current prices are not available for this product yet.

Vetri SAMe

FoodScience, LLC (VetriScience & Pet Naturals)

Vetri SAMe

Tablet

NASC-certified manufacturer

Verified product details

  • 90/225 SAMe per 1 Tablet
  • Form: Tablet
  • Serving size: 1 Tablet

Retailer availability

Retailer links and current prices are not available for this product yet.

Zentonil Advanced

Vetoquinol USA, Inc.

Zentonil Advanced

Tablet

NASC-certified manufacturer

Verified product details

  • 100/200/400 SAMe per 1 Tablet
  • Form: Tablet
  • Serving size: 1 Tablet

Retailer availability

Retailer links and current prices are not available for this product yet.

Why are some supplements not listed?

A product can be omitted when the manufacturer is not currently NASC certified, the ingredient lacks published support for this specific goal and species, or its record is still awaiting editorial verification.

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